Cefixime Trihydrate is in a group of drugs called cephalosporin antibiotics. Cefixime is used to treat many different types of infections caused by bacteria. Your symptoms may get better before the infection is completely treated. Cefixime will not treat a viral infection such as the common cold or flu.
It has been demonstrated by recent studies that Cefixime shows significantly better symptoms relief with the modest improvement of bacterial infection.
Indications and Usage:
It is used to treat number of Bacterial infections including:
● Urinary tract infections caused by Escherichia coli and Proteus mirabilis.
● Otitis media caused by Haemophilus influenza.
● Onsillitis caused by S. pyogenes.
● Uncomplicated gonorrhea caused by Neisseria gonorrhoeae.
Pharmacodynamics:
Cefixime trihydrate, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
Mode of Action:
Like all beta-lactam antibiotics, cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall , thus causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.
Drug Interactions:
BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT CHILD HAS NOW OR HAS HAD.
Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications. Probenecid may increase the serum level of cefixime.
Contraindications:
Cefixime Trihydrate is contraindicated for use in the following conditions:
● Caution when used during pregnancy.
● Caution when used during lactation.
● Hypersensitivity to cephalosporin.
Adverse Effects:
The most commonly reported adverse effects are:
● Fever
● Sore throat
● Headache
Conclusion:
From the above discussion, it can be concluded that this Cefixime dry Syrup could improve the quality of life of children with Bacterial infections We are making superior quality of Cefixime dry Syrup that is used to treat a variety of infections which is caused by Bacteria. Our offered syrup is processed using high grade chemical compounds by our experienced quality controllers that ensure its quality, purity and chemical properties. Highly treasured among the clients for its reliability, accurate composition, excellent physical and purity, this dry syrup is offered to our esteemed clients at the market leading prices.