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Melatonin is a promising supplement useful in solving problems of:-
  • Sleep wake cycle (pattern of alternating sleep and wakefulness roughly for 8 hours and 16 hours day time activity)
  • Sleeping disorders (insomnia)
  • Internal body clock as cicardian rhythm (this tells our body to sleep and rise)
  • It is exceptionally useful in reducing or preventing jet lag (extreme tiredness after long time across different zones
  • It plays a crucial role in neurodegenerative disorders- after middle age, the level of melatonin decreases resulting in oxidative stress. So, melatonin has been confirmed as free radical scavengers and antioxidant not only in-vitro but also in several in-vivo studies. It is safer as compared to other antioxidants
Melatonin soft gel capsule is more effective as compared to other dosage forms of melatonin. Soft gel capsules improved the bioavailability (absorption) of melatonin.


What is Melatonin:
Melatonin is a natural hormone made by the pineal gland, a small gland in the brain. It helps to control your sleep and wake cycles. During the day time it is inactive but during darkness the pineal is turned on that is why it is called "DRACULA OF HORMONES" and begins to produce melatonin actively. Then, the melatonin is released into the blood. This occurs around 9 p.m. As a result, it rises sharply and feels less alert. Levels of melatonin remain high throughout night before the light of a new day.

Culprits of Low Melatonin Levels :
  • Alcohol
  • Caffeine
  • Cigarettes
  • Antidepressants
  • Frequent stress
  • NSAID anti-inflammatory medication

Indications:
It is effective for:
  • Trouble falling asleep
  • Sleep disorders in blind people
  • Sleeping problems in people with sleep-wake cycle disturbances
  • Reducing the sleep interruptions in elderly people with reduced rapid eye moment (rapidly eye shifting beneath closed lids during sleeping)
  • Insomniac patients
  • People who work night shifts
  • Strengthening your immune system- melatonin is important for the proper functioning of your immune system, scavenging free radicals, reducing inflammation and helping your body to rid itself of cancer cells

Mechanism of action:
Melatonin's main job in the body is to regulate night and day cycles or sleep-wake cycles. Darkness causes the body to produce more melatonin, which signals the body to prepare for sleep. Light decreases melatonin production and signals the body to prepare for being awake. Some people who have trouble sleeping have low levels of melatonin. It is thought that adding melatonin from supplements might help them sleep and also regulating their body clock.

Side Effects:
  • Sleepines
  • Dizziness
  • Headache

Use cautiously in people:
  • Who have or are at risk of changes in hormone levels, eye disorders, frequently feeling cold, genital or urinary disorders (including children with a history of bedwetting), heart disease, hyperactivity, immune disorders, inflammatory disorders, mental disorders, muscle control problems, nervous system disorders, seizures, skin disorders, and stomach and intestinal problems
  • Taking agents that affect the immune system, anti-inflammatory agents, or hormonal agents
  • In breastfeeding women, due to a lack of safety information
  • Avoid in women who are pregnant or trying to get pregnant. Melatonin may decrease sex drive, increase the risk of developmental disorders, and reduce ovarian function
  • Avoid in people with known allergy or sensitivity to melatonin or related products

Storage:
Store in a cool, dry & dark place. Protected from direct sunlight.